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/
Simparica Trio
/
Large Flea, Tick and Worming Chew (20-40kg)

Large Flea, Tick and Worming Chew (20-40kg)

Simparica Trio
4.8
(
762
)
Simparica Trio™ for Dogs builds on Simparica's proven flea and tick protection by adding heartworm prevention and intestinal worm treatment in one monthly beef-flavoured chew. Combining sarolaner, moxidectin and pyrantel, it delivers broad-spectrum protection against both external and internal parasites in a single dose. Each chew protects against paralysis ticks, brown dog ticks and bush ticks, kills fleas within 3 hours, prevents heartworm disease, and treats and controls roundworms and hookworms. Fleas are killed before they can lay eggs, helping to break the flea life cycle and prevent home infestations. Safe for puppies from 8 weeks of age and weighing at least 1.3 kg, with six weight-based sizes available up to 60 kg.
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Overview

Simparica Trio™ for Dogs builds on Simparica's proven flea and tick protection by adding heartworm prevention and intestinal worm treatment in one monthly beef-flavoured chew. Combining sarolaner, moxidectin and pyrantel, it delivers broad-spectrum protection against both external and internal parasites in a single dose.

Each chew protects against paralysis ticks, brown dog ticks and bush ticks, kills fleas within 3 hours, prevents heartworm disease, and treats and controls roundworms and hookworms. Fleas are killed before they can lay eggs, helping to break the flea life cycle and prevent home infestations.

Safe for puppies from 8 weeks of age and weighing at least 1.3 kg, with six weight-based sizes available up to 60 kg.

Ingredients

Active: Sarolaner, Moxidectin, Pyrantel (as Embonate). Inactive: Butylhydroxytoluene, Calcium Hydrogen Phosphate Anhydrous, Confectioner's Sugar, Gelatin, Glucose Liquid, Hydrolysed Vegetable Protein, Hydroxypropylcellulose, Hypromellose, Lactose Monohydrate, Magnesium Stearate, Maize Starch, Meglumine, Pigment Blend 018 (Allura Red, Indigo Carmine, Sunset Yellow FCF), Pork Liver Powder, Silica Colloidal Anhydrous, Sodium Starch Glycolate Type A, Wheat Germ.

Ingredient images are illustrative only and may not represent the exact source or form used by manufacturers.
Black and white line drawing of the Sarolaner chemical structure with hexagonal and pentagonal rings for dog parasite control
Sarolaner
Sarolaner
Summary
Sarolaner is an isoxazoline compound used in oral flea and tick preventatives for dogs. It kills parasites by blocking inhibitory neurotransmitter receptors in their nervous systems, providing rapid and sustained monthly protection.
Moxidectin chemical structure in black lines with rings and chains on a white background, used in dog parasite treatments
Moxidectin
Moxidectin
Summary
Moxidectin is a macrocyclic lactone used to prevent heartworm and treat a range of internal and external parasites. It works by disrupting nerve signal transmission in parasites, and is available in both oral and topical formulations.
Black and white chemical structure diagram of pyrantel, displaying its molecular bonds and ring formations
Pyrantel
Pyrantel
Summary
Pyrantel is an anthelmintic commonly used to treat roundworm and hookworm infections in dogs. It causes spastic paralysis in susceptible worms by acting as a nicotinic receptor agonist, allowing them to be expelled through normal bowel movements.
Off-white, fine powder form of butylhydroxytoluene ingredient used in dog supplements and pet food
Butylhydroxytoluene
Butylhydroxytoluene
2,6-Di-Tert-Butyl-4-Methylphenol, BHT, E321, 2,6-Di-Tert-Butyl-P-Cresol
Summary
Butylhydroxytoluene (BHT) is a synthetic antioxidant derived from petroleum sources. It is primarily included in pet food to prevent the oxidation of fats and oils, thereby extending shelf life and maintaining nutritional quality. BHT is not used in its raw chemical state; instead, it is incorporated as a purified compound specifically formulated for food safety and effective preservation.
Why it's used?
Butylhydroxytoluene is included as a synthetic antioxidant to extend shelf life by preventing the oxidation of fats and oils in pet food. Its use helps maintain product stability and freshness during storage and distribution.
Fine white powder with a slightly grainy texture and diagonal ridges, representing Dicalcium Phosphate Anhydrous
Dicalcium Phosphate Anhydrous
Dicalcium Phosphate Anhydrous
Dibasic Calcium Phosphate, Dicalcium Phosphate, Calcium Phosphate Dibasic, E341(ii)
Summary
Calcium hydrogen phosphate anhydrous is a mineral-derived compound commonly included in pet food formulations. It serves as a source of both calcium and phosphorus, essential minerals that support healthy bone development and metabolic functions. Rather than being used in its natural, raw mineral state, calcium hydrogen phosphate anhydrous is utilised in a purified, compound form to optimise safety, stability, and bioavailability for pets.
Why it's used?
Calcium hydrogen phosphate anhydrous is included as a cost-effective mineral supplement to provide essential calcium and phosphorus for skeletal health. It also serves as a functional ingredient to help balance the overall mineral content in the formulation.
Fine white powdered sugar with a soft, fluffy texture shown in close-up, suitable for dog health ingredient context
Powdered Sugar
Powdered Sugar
Confectioners' Sugar, Icing Sugar, 10X Sugar, E174
Summary
Powdered sugar is a finely ground form of sucrose derived from plant sources, typically sugarcane or sugar beet. It serves primarily as a carbohydrate source, providing quick energy. In pet food, powdered sugar is used to enhance palatability and texture. This ingredient is utilised in its processed, powdered form rather than as raw sugar crystals, ensuring even distribution and ease of mixing.
Why it's used?
Powdered sugar is included as a cost-effective sweetener and palatability enhancer, making the product more appealing to pets. It may also contribute to product texture and consistency in certain formulations.
Fine, pale yellow gelatine powder with a smooth, slightly grainy texture, commonly used in dog supplements
Gelatine
Gelatine
Gelatin, E441, Hydrolysed Collagen, Collagen Hydrolysate
Summary
Gelatine is a protein derived from animal collagen, typically sourced from the skin, bones, and connective tissues of cattle or pigs. It serves as a gelling agent, providing structure and texture to pet foods while also contributing to protein content. Gelatine is not used in its raw animal form but is processed and purified to ensure safety, digestibility, and optimal functional performance.
Why it's used?
Gelatine is included as a functional binding and gelling agent to improve the texture and cohesiveness of pet food products. It also serves as a cost-effective protein source that can enhance palatability.
Clear, glossy puddle of glucose liquid with a smooth, syrupy texture on a white background
Glucose Liquid
Glucose Liquid
Glucose Syrup, Liquid Glucose Syrup, Starch Syrup, E965 Syrup
Summary
Glucose liquid is a carbohydrate ingredient derived from plant sources, typically corn or wheat, and is presented as a clear, viscous syrup. Its primary purpose in pet food is to provide a readily available source of energy and to enhance palatability. Rather than occurring in its natural crystalline form, glucose is utilised in a liquid state to ensure ease of mixing and consistent absorption.
Why it's used?
Glucose liquid is included as a cost-effective carbohydrate source that provides readily available energy and enhances palatability. It may also function as a humectant, helping to maintain product moisture and texture stability.
Too vague to identify
Hydrolysed Vegetable Protein
Hydrolysed Vegetable Protein
Acid-Hydrolysed Vegetable Protein, Enzymatically Hydrolysed Vegetable Protein, HVP, Plant Protein Hydrolysate
Summary
Hydrolysed vegetable protein is a plant-derived ingredient produced by breaking down vegetable proteins into smaller peptides and amino acids through hydrolysis. Its primary purpose is to enhance palatability and provide a readily digestible source of protein. Rather than being used in its original whole food form, it is utilised in a hydrolysed state to optimise digestibility and reduce allergenic potential.
Why it's used?
Hydrolysed vegetable protein is included as a cost-effective source of amino acids and to enhance palatability through the creation of savoury flavours. It also allows manufacturers to optimise protein content while maintaining a desirable product texture and appearance.
Fine white powder with a slightly granular texture, showing the dog supplement ingredient hydroxypropylcellulose
Hydroxypropylcellulose
Hydroxypropylcellulose
Cellulose, Hydroxypropyl Ether, E463, Klucel
Summary
Hydroxypropylcellulose is a plant-derived cellulose derivative commonly used in pet food as a functional ingredient. It serves primarily as a thickener, stabiliser, and binder, helping to maintain product texture and consistency. Hydroxypropylcellulose is not used in its natural cellulose form; instead, it is chemically modified to enhance solubility and functionality, ensuring safe and effective incorporation into pet food formulations.
Why it's used?
Hydroxypropylcellulose is included as a functional additive to improve texture and binding in pet food formulations, ensuring product consistency and stability. It also acts as a thickening agent, helping to maintain the desired shape and moisture retention in processed products.
Fine white hypromellose powder with a soft, slightly textured surface, used in dog health supplements
Hypromellose
Hypromellose
Hydroxypropyl Methylcellulose, E464, HPMC, Cellulose Hydroxypropyl Methyl Ether
Summary
Hypromellose is a semi-synthetic, plant-derived compound created from cellulose, a natural polymer found in plant cell walls. It is primarily used in pet food as a binder, thickener, or coating agent to improve texture and stability. Hypromellose is not used in its raw plant form; instead, it is processed and modified to achieve the desired functional properties for safe and effective use in formulations.
Why it's used?
Hypromellose is included as a processing aid and coating agent to improve the stability and shelf life of certain nutrients or medications within pet food formulations. It also helps control the release of active ingredients in specialised diets or supplements.
Fine white powder texture of lactose monohydrate, a common ingredient in dog supplements and medications
Lactose Monohydrate
Lactose Monohydrate
Milk Sugar Monohydrate, Saccharum Lactis Monohydricum, E966 Monohydrate, β-D-Galactopyranosyl-(1→4)-D-Glucose Monohydrate
Summary
Lactose monohydrate is a carbohydrate derived from milk, making it an animal-origin ingredient. It serves primarily as an energy source and can also function as a palatability enhancer in pet foods. Lactose is not used in its raw, natural state; instead, it is utilised as lactose monohydrate, a purified and stable compound, to ensure consistency and digestibility in formulated diets.
Why it's used?
Lactose monohydrate is included as a cost-effective carbohydrate source and to enhance palatability in pet food formulations. It may also serve as a carrier for flavours or active compounds, optimising ingredient dispersion.
Fine white powder with a soft, smooth texture representing magnesium stearate used in dog supplements
Magnesium Stearate
Magnesium Stearate
Octadecanoic Acid Magnesium Salt, Magnesium Octadecanoate, E470b, Stearic Acid Magnesium Salt
Summary
Magnesium stearate is a compound derived from the mineral magnesium and stearic acid, a fatty acid typically sourced from plant or animal origins. It is primarily used as a flow agent in pet food manufacturing, ensuring even mixing and preventing clumping. Magnesium stearate is not used in its natural metallic form; instead, it is utilised as a safe, bioavailable compound to optimise processing.
Why it's used?
Magnesium stearate is included as a flow agent to prevent ingredients from clumping and to optimise the manufacturing process by ensuring consistent mixing and tablet formation. Its use supports production efficiency and product uniformity rather than providing direct nutritional benefits.
Fine white powdery maize starch with a soft, slightly uneven texture, commonly used as a dog food ingredient
Maize Starch
Maize Starch
Corn Starch, Zea Mays Starch, E1401, Cornflour
Summary
Maize starch is a carbohydrate ingredient derived from the endosperm of maize (corn) kernels, making it a plant-based component. It serves primarily as a source of easily digestible energy and acts as a functional binder in pet food formulations. Maize starch is utilised in its processed, refined form rather than as whole maize, ensuring consistency, digestibility, and suitability for pet nutrition.
Why it's used?
Maize starch is included as a cost-effective carbohydrate source that provides energy and helps bind kibble, optimising texture and processing efficiency. Its neutral flavour and label-friendly profile also support product stability and consumer acceptance.
Fine white crystalline powder of meglumine with a slightly grainy texture, used in dog health supplements
Meglumine
Meglumine
N-Methylglucamine, Esglumin, N-Methyl-D-Glucamine, 1-Deoxy-1-(Methylamino)-D-Glucitol
Summary
Meglumine is a synthetic compound derived from sorbitol, a plant-based sugar alcohol. In pet food, its primary function is to act as a stabiliser or solubilising agent, enhancing the bioavailability of certain nutrients and medications. Meglumine is not used in its natural form but is specifically manufactured for safe inclusion, ensuring optimal absorption and efficacy within formulated diets.
Why it's used?
Meglumine is included as a stabilising agent to enhance the solubility and stability of certain nutrients or additives in pet food formulations. Its use helps optimise product consistency and shelf life without significantly impacting palatability or nutritional value.
Pigment Blend 018 pale pink powder with fine texture and subtle diagonal ridges, shown in close-up detail
Pigment Blend 018
Pigment Blend 018
Pigment Mixture 018, Colourant Blend 018, Colour Blend 018, Pigment Composite 018
Summary
Pigment Blend 018 is a formulated mixture of colourants derived from both natural and synthetic sources, designed specifically for use in pet food. Its primary purpose is to enhance or standardise the visual appearance of the final product, ensuring consistency and consumer appeal. Pigment Blend 018 is not used in its raw or natural state; instead, it is utilised as a carefully measured, food-grade compound to ensure safety and uniformity.
Why it's used?
Pigment Blend 018 is included to standardise and enhance the visual appearance of the pet food, ensuring consistent colour across batches. This supports consumer appeal and brand recognition without affecting the nutritional profile of the product.
Fine, light brown pork liver powder in a soft, crumbly mound on a plain background, ideal for dog nutrition
Pork Liver Powder
Pork Liver Powder
Porcine Liver Powder, Sus Scrofa Liver Powder, Dehydrated Porcine Liver, Freeze-Dried Porcine Liver
Summary
Pork liver powder is a dehydrated and finely ground product derived from the liver of pigs, making it an animal-based ingredient. It is primarily included in pet food for its rich content of high-quality protein, essential vitamins, and minerals, particularly vitamin A and iron. Rather than being used fresh, pork liver is processed into a powder form to optimise shelf life and nutrient stability.
Why it's used?
Pork liver powder is included as a highly palatable protein source that enhances flavour and encourages consumption. It also provides essential nutrients, supporting the product’s nutritional profile for marketing and labelling purposes.
Fine white powder texture of Silica Colloidal Anhydrous, a common ingredient in Australian dog health supplements
Silica Colloidal Anhydrous
Silica Colloidal Anhydrous
Colloidal Silicon Dioxide, Fumed Silica, Synthetic Amorphous Silica, E551
Summary
Silica Colloidal Anhydrous is a purified, amorphous form of silicon dioxide derived from mineral sources. It serves primarily as an anti-caking agent, helping to maintain the free-flowing nature of powdered pet food ingredients. Silica is not used in its natural, raw mineral state; instead, it is utilised in a processed, colloidal anhydrous form to ensure safety, stability, and optimal absorption.
Why it's used?
Silica colloidal anhydrous is included as an anti-caking agent to improve the flow and handling of powdered ingredients during manufacturing. Its use helps maintain product consistency and prevents clumping, supporting efficient processing and packaging.
Fine white powder texture of sodium starch glycolate, a common dog supplement ingredient in Australia
Sodium Starch Glycolate
Sodium Starch Glycolate
Sodium Carboxymethyl Starch Type A, SSG Type A, Carboxymethyl Starch Sodium Type A, E468 Type A
Summary
Sodium starch glycolate Type A is a plant-derived ingredient produced by modifying starch, typically from potatoes or corn, with sodium salts. It functions primarily as a disintegrant, helping kibble or treats break down more easily for improved digestibility. Rather than being used in its natural starch form, it is utilised as a chemically modified compound to optimise its functional properties in pet food formulations.
Why it's used?
Sodium Starch Glycolate Type A is included as a functional processing aid to improve kibble texture and optimise moisture retention. Its use can also enhance product stability by acting as a disintegrant, ensuring consistent quality during storage and handling.
Fine, light brown wheat germ powder with a soft, grainy texture displayed in a neat circular pile on a plain background
Wheat Germ
Wheat Germ
Triticum Vulgare Germ, Triticum Vulgare Embryo, Wheat Embryo, Triticum Germ
Summary
Wheat germ is the nutrient-rich embryo of the wheat kernel, derived from the plant Triticum aestivum. It is included in pet food primarily as a source of high-quality protein, essential fatty acids, and B vitamins, supporting energy metabolism and skin health. Wheat germ is used in its natural form, ensuring optimal nutrient availability and digestibility for pets.
Why it's used?
Wheat germ is included as a cost-effective source of plant-based protein, vitamins, and essential fatty acids, contributing to the nutritional profile of the product. It also serves as a label-friendly ingredient that appeals to health-conscious consumers.

About

Brand
Simparica Trio
Company
Zoetis
Manufactured
United States
Type
Chew
Life Stage
All Life Stages
Breed Size
Medium, Large
Processing Level
High

PRODUCT TAGS

Chewable Treatment
Flea
Tick
Mites
Heartworm
Roundworm
Hookworm
1 Month Protection
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About the Brand

Simparica Trio

Simparica Trio offers comprehensive monthly protection against fleas, paralysis ticks, heartworm, and intestinal worms in a single tasty chew. Explore the full range of Simparica Trio sizes to find the vet recommended all in one defence that keeps your dog safe year round.

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Large Flea, Tick and Worming Chew (20-40kg)
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4.8
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